Magnetic Field-Enabled Piezocatalysis: Mechanisms, Materials, and Emerging Biomedical Applications
DOI:
https://doi.org/10.64509/jim.11.66Keywords:
Magnetostrictive Effect, Piezoelectric Effect, Piezocatalytic TherapyAbstract
Magnetic field-enabled piezocatalytic therapy represents an emerging frontier in non-invasive biomedical treatments, integrating the principles of magnetostriction, piezoelectricity, and magnetoelectric coupling to remotely drive reactive oxygen species (ROS) generation for therapeutic applications. In this Perspective, we first elucidate the fundamental mechanisms underlying magnetostrictive deformation, piezoelectric polarization, and strain-mediated magnetoelectric coupling, highlighting how mechanical energy derived from magnetic fields can be efficiently converted into localized electric potentials and catalytic activity. We then examine the design and function of magnetostrictive-piezoelectric composite materials, emphasizing core-shell architectures, interface engineering, and nanostructuring strategies that enhance ROS production. Recent advancements in magnetic field-enabled piezocatalytic tumor inhibition, along with comparisons to conventional ultrasound-activated approaches, are discussed. Finally, we outline critical challenges and future directions from the perspectives of material optimization, biocompatibility, mechanistic elucidation, and in vivo evaluation, aiming to guide the rational development of next-generation remotely controllable piezocatalytic therapeutics. This Perspective paper presents a conceptual framework for the design and implementation of magnetic field-enabled piezocatalysis, establishing a connection between materials science and biomedical innovation.
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